1820: Sophia Ashmore-Percy reluctantly accompanies her husband James to a remote Greek island, where he searches for rare biological specimens. Once there, however, she sets on her own voyage of discovery—stumbling across the very creature he is looking for, making an unexpected connection with a local woman, and ultimately reconsidering her marriage, life, and own desires.

Decades later, audiologist Henry Latimer is sent to the home of industrialist Sir Edward Ashmore-Percy and tasked with curing the man’s young daughter, Philomel, of her deafness. But Henry, eager to escape a troubled past, quickly becomes obsessed with the fascinating nature of Sir Edward’s business: spinning silk with a rare and magical breed of spiders. The extraordinary silk shields sound, offering respite from bustling streets and noisy neighbors. The result is instant tranquility, as wearers experience a soothing calmness.

Yet, those within earshot of the outward-facing silk are subjected to eerie murmurs that amplify with proximity. Bystanders suffer the consequences of this unnerving phenomenon, manifesting in physical and mental afflictions ranging from headaches and drowsiness to severe cases of madness. As Henry becomes entangled in the allure of the silk and Sir Edward’s charm, he glimpses a more sinister family history. The closer he ventures into the inner circle of Carthmute House, the more he unravels the horrifying underbelly of the silk business.